It was reported, a natural chemical mangiferin, found in the stem bark of the mango tree inhibits tumor growth in early and late stages of cancer.
Mangiferin imparts cardiotonic, diuretic and hepato-protective properties to the mango. Mangiferin concentration of 4.4 ug/g was determined in a mango puree.
Mangiferin has been reported to show protective against CCl4 induced liver injury in rats.
Mangiferin was tested in bowel carcinogenesis of a male rat and showed great inhibitory effects and can be classified as a potential chemopreventive agent.
Xanthone mangiferin has been shown to lower blood glucose levels for type 2 diabetes. It improve hyperinsulinemia, possible by decreasing insulin resistance, and to exhibit alpha-glucosidase and aldose reductase-inhibitory activities.
Mangiferin, together with epigallocatechin gallate has been found to be able to have a protective effect on lipid peroxidation in red blood cells. Possibly due to its antioxidant activity.
Mangiferin in mango