Chylomicrons are produced in the intestinal mucosa in response to the ingestion of dietary fat. In man, chylomicrons are normally absent in plasma after an overnight (12-16 hr) fast, even in subjects given diets consisting nearly entirely of fats.
Chylomicrons play an important role in transporting dietary triglycerides from intestine to the dispose tissue for storage; and to muscle or heart for their energy needs.
More than one-half of the lipids in chylomicron and VLDL are triacylglycerol.
Main sites of metabolism of chylomicrons are adipose tissue and skeletal muscle. The half-life of chylomicrons in blood is about 1 hour.
Lipoprotein of chylomicrons