Vitamin B1 or thiamin molecule comprises substituted pyrimidine and thiazole moieties linked by a methylene bridge.
Vitamin B1 was given the name thiamin because it contains a thiol (sulfur) group and an amine (nitrogen) group.
Thiamin functions as a coenzyme in the metabolism of carbohydrates and branched chain amino acids. Although thiamin, per se, is not an energy-yielding nutrient, its coenzyme form TPP is needed for ATP production.
TPP or thiamin triphosphate functions as a coenzyme, catalyzing reactions that enable the body to use glucose, amino acids and fatty acids for energy.
Absorption of thiamin occurs mainly in the jejunum, at lower concentration as an active, carrier mediated system involving phosphorylation and at higher concentration by passive diffusion.
The classic pathological condition rusting from a gross deficiency of thiamin in humans is beriberi, which is prevalent in Far Eastern populations where unfortified polished rice is staple diet.
Vitamin B1 in human body
The Most Popular Posts
-
Crude fat is the term used to refer to the crude mixture of fat-soluble material present in a sample. Crude fat also known as the ether ext... -
Ash or mineral content is the portion of the food or any organic material that remains after it is burned at very high temperatures. The a... -
Crude fiber is a measure of the quantity of indigestible cellulose, pentosans, lignin, and other components of this type in present foods. ... -
Gelatinization occurs when starch granules are heated in a liquid. It is responsible for the thickening of food systems. The process is an i... -
Density is the weight of a substance per unit of volume, while specific gravity is the ratio between the density of the substance and that o...